Welcome to the Verdoes Lab website!
Our research team is part of the Department of Tumor Immunology of the Radboud Institute for Molecular Life Sciences, Radboudumc in Nijmegen and develops novel tools to restore and potentiate our immune system in the battle against cancer. For this purpose, we combine the fields of chemistry, molecular biology, genetics and immunology to deepen our understanding of the interplay between our immune system and cancer.
Cancer is a complex disease with multiple defence mechanisms which hamper effective functioning of our immune system. Therefore, our lab works on multiple lines of attack to defeat cancer. On one hand, we aid recognition and eradication of tumor cells by the design and development of targeted nanovaccines. On the other, we break down the defensive wall of the tumor with our own designed compounds which can target, visualize and kill immunosuppressive cells.
Together, these chemistry-based precision immunotherapy approaches can tip the balance from cancer tolerance to cancer immunity without adverse side effect.
Our research is funded by the following organizations: